Hodgkin Lymphoma Treatment

In this article, we have covered the following:

  • Best Hospitals for Hodgkin Lymphoma Treatment in India
  • Top Oncologists expertised in Hodgkin Lymphoma Treatment
  • Cost of Hodgkin Lymphoma Treatment
  • Understanding Hodgkin Lymphoma

Best Doctors and Hospitals for Hodgkin Lymphoma Treatment in India

Following is a list of the most reputed specialists in India for Hodgkin Lymphoma Treatment.
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Doctor ImageDr. NameSpecialtyHospital AssociatedContact DoctorCity
Dr. Rahul BhargavaDr. Rahul BhargavaHaemato OncologistFortis Memorial Research InstituteGurgaon
Dr. Vikas DuaDr. Vikas DuaHaemato OncologistFortis Memorial Research InstituteGurgaon
Dr. Prantar ChakrabartiDr. Prantar ChakrabartiHaemato OncologistFortis Hospital AnandapurKolkata
Dr. satya prakash yadavDr. Satya Prakash YadavHaemato OncologistMedanta - The MedicityGurgaon
Dr Hari GoyalDr. Hari GoyalHaemato OncologistArtemis HospitalGurgaon
Dr Santanu SenDr. Santanu Sen Haemato OncologistKokilaben Dhirubai Ambani HospitalMumbai
Dr. Shishir SethDr. Shishir SethHaemato OncologistIndraprastha Apollo HospitalNew Delhi
Dr Dharma ChoudharyDr. Dharma ChoudharyHaemato OncologistBLK Super Specialty HospitalDelhi
Dr. Sharat DamodarDr. Sharat DamodarBone Marrow TransplantNarayana Multispeciality HospitalBangalore

Cost of Treatment

Unfortunately, we are not able to share the cost of this treatment as we are still awaiting response from few hospitals before publishing the cost. However, you may share your medical reports and we will share the cost of treatment from the hospital recommended for you.

Understanding Hodgkin Lymphoma

  • It is a potentially curable lymphoma.
  • The etiology of Hodgkin lymphoma is unknown. Infectious agents, particularly Epstein-Barr virus (EBV), may be involved in the pathogenesis
  • HIV-positive patients also have a higher incidence of Hodgkin lymphoma
  • Approximately 1% of patients with Hodgkin lymphoma have a family history of the disease
  • Nonsclerosing Hodgkin lymphoma (NSHL) has been shown to be one of the most heritable types of neoplasm, with a 100-fold increased risk in identical twins
  • Hodgkin lymphoma incidence rates vary by race and sex. Incidence is higher in males than in females
  • The sex predilection is most pronounced in children, with 85% of cases affecting boys.The lowest incidence is found in Asians and Pacific Islander
  • The initial peak is in young adults (15-34 years) and older adults (>55 years)

Types of Hodgkin Lymphoma

Hodgkin lymphoma into the following types

  • Nodular sclerosing (60-80%)- common in adolescent & young
  • Mixed cellularity (15-30%)- common in HIV patients
  • Lymphocyte depleted (1%)- old age & HIV patients
  • Lymphocyte rich (5%)
  • Nodular lymphocyte predominant(5%)

Signs & Symptoms of Hodgkin Lymphoma

Features of Hodgkin lymphoma include the following:

  • Asymptomatic lymph node enlargment
  • Unexplained weight loss, fever with night sweats
  • Chest pain, cough,  shortness of breath
  • Pruritus
  • Pain at sites of nodal disease
  • Back or bone pain
  • Palpable, painless lymph node enlargment in the cervical area, axilla, or inguinal area
  • Spleen enlargment or liver enlargment
  • Superior vena cava syndrome may develop
  • Central nervous system symptoms

Diagnosis of Hodgkin Lymphoma

Laboratory tests include the following:

  • Complete blood cell count
  • Erythrocyte sedimentation rate
  • Lactate dehydrogenase
  • Serum creatinine
  • Alkaline phosphatase
  • A test for HIV is important because antiviral therapies can improve disease outcomes in HIV-positive patients ; screening for hepatitis B and C should also be considered

Imaging studies include the following:

  • Chest x ray
  • Computed tomography: Chest radiography has been largely replaced by CT scanning
  • Positron emission tomography: Considered essential to the initial staging of Hodgkin lymphoma

A histologic diagnosis of Hodgkin lymphoma is always required. An excisional lymph node biopsy is recommended

When a patient presents with neck lymphadenopathy and risk factors for a head and neck cancer, a fine-needle aspiration is usually advised as the initial diagnostic step, followed by biopsy.

Bone marrow involvement is more common in elderly patients and those with advanced-stage disease,so bone marrow test is indicated in those cases.

Central nervous system evaluation by lumbar puncture and magnetic resonance imaging should be performed if symptoms or signs of CNS involvement are present.

Involvement of the liver or the bone marrow is considered stage IV disease. For staging classifications, the spleen is considered to be a lymph node area.

A or B designations denote the absence or presence of B symptoms. A “B” designation includes the presence of one or more of the following:

  • Fever (temperature >38 degree C)
  • Drenching night sweats
  • Unexplained loss of more than 10% of body weight within the preceding 6 months
  • “A” means there is absence of the above

Management of Hodgkin Lymphoma

General treatment principles include the following:

1. Radiation therapy

  • Extended-field radiation (EFRT): Radiation on clinically involved nodes but also on the adjacent clinically uninvolved nodes. EFRT is not used in modern treatment of Hodgkin lymphoma
  • Involved-field radiation (IFRT): Radiation field that involve all of the clinically affected regions
  • Involved-site radiation (ISRT)
  • Involved-node radiation (INRT): it is still considered experimental

ISRT is largely replacing IFRT.

2. Induction chemotherapy

3. Salvage chemotherapy

4. Hematopoietic stem cell transplantation

High-dose chemotherapy (HDC) at doses that ablate the bone marrow is feasible with reinfusion of the patient’s previously collected hematopoietic stem cells (autologous transplantation) or infusion of stem cells from a donor source (allogeneic transplantation)

Toxicities associated with treatment regimens include the following:

  1. Hematologic toxicity
  2. Pulmonary toxicity
  3. Cardiac toxicity
  4. Infections
  5. Cancer: Increased risk of secondary cancers, particularly breast cancer in young women treated with radiation
  6. Neurologic: Chemotherapy-induced neuropathy, muscular atrophy
  7. Psychiatric: Depression and anxiety related to diagnosis


The most commonly used prognostic system is the International Prognostic System (IPS), which uses the following variables to determine prognosis

  • Serum albumin less than 4 g/dL
  • Hemoglobin less than 10.5 g/dL
  • Male sex
  • Age of 45 years or older
  • Stage IV disease
  • White blood cell (WBC) count greater than 15,000/mm 3
  • Absolute lymphocyte count less than 600/mm 3, less than 8% of the total WBC count, or both

Note (for foreign patients):

Besides South Asian countries (Afghanistan, Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka), every year, India gets thousands of medical tourists from African countries- Nigeria, Kenya, Ethiopia, Sudan, Uganda, Ghana, Somalia,Gambia etc and Middle Eastern countries like Iraq, Iran, Saudi Arabia, Oman, UAE, Yemen etc. Hence, if you are a citizen of any of these countries, there is good likelihood that you will be meeting some fellow citizens or same language speakers in the major hospitals in India. Almost all the top hospitals have translators for people of these region. Our patient support team is also well placed to assist you.

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